PakMedicine Clinical Courses

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PakMedicine's high-yield guide to neuroanatomy for USMLE Step 1 is built around the one skill the exam tests most: reading a clinical vignette and localising the lesion. It is written for medical students and graduates in Pakistan and across Asia who are preparing for the United States Medical Licensing Examination.

Each chapter opens with learning objectives and uses colour-coded original figures: red for motor pathways and arteries, blue for sensory pathways and veins, and green for autonomic pathways. Clinical correlation, high-yield and worked example boxes show how the anatomy appears in exam questions.

What's inside

  • 509 pages, first edition 2026
  • 18 chapters in five parts, from foundations to integration
  • 154 original figures
  • 510 board-style MCQs with full explanations (25 per chapter)
  • 10 lesion-localisation case walkthroughs
  • A 60-question comprehensive exam, summary tables and an index
  • South Asia Focus boxes on conditions common in Pakistan, such as TB meningitis and neurocysticercosis, taught to the USMLE standard

Who it is for

USMLE Step 1 candidates, MBBS students who find neuroanatomy hard, and graduates revising for other exams that test lesion localisation.

How to read it

The book opens in our secure online reader on phone, tablet or laptop, with one year of access. Try the free 10-page preview first. A suggested plan is one chapter every two days, then a second pass of the rapid reviews, then the comprehensive exam in your final week.

Independent exam preparation. USMLE® is a programme of FSMB and NBME, which are not affiliated with and do not endorse this book.

Contents

  1. Chapter 1: Organisation and Gross Anatomy of the Brain Page 14
  2. Chapter 2: Development of the Nervous System and Congenital Malformations Page 35
  3. Chapter 3: Neurohistology Page 57
  4. Chapter 4: Meninges, Ventricles, Cerebrospinal Fluid and CNS Infections Page 82
  5. Chapter 5: Blood Supply, Stroke Syndromes and Intracranial Haemorrhage Page 113
  6. Chapter 6: Spinal Cord and Its Tracts Page 140
  7. Chapter 7: Spinal Cord and Peripheral Nerve Lesions Page 162
  8. Chapter 8: Brainstem Page 186
  9. Chapter 9: Cranial Nerves and the Trigeminal System Page 211
  10. Chapter 10: Brainstem Lesions and Syndromes Page 238
  11. Chapter 11: Diencephalon: Thalamus, Hypothalamus and Internal Capsule Page 263
  12. Chapter 12: Special Senses: Vision, Hearing and Balance Page 285
  13. Chapter 13: Smell, Taste and the Limbic System Page 310
  14. Chapter 14: Motor Control: Basal Nuclei and Cerebellum Page 331
  15. Chapter 15: Autonomic Nervous System Page 354
  16. Chapter 16: Neurotransmitters and Their Pathways Page 385
  17. Chapter 17: Cerebral Cortex: Localisation, Language, Epilepsy and Sleep Page 409
  18. Chapter 18: Localising the Lesion: Ten Case Walkthroughs Page 435
  19. Comprehensive examination (60 questions) Page 457

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